Original scientific paper
Bone Fragility Fractures in Hemodialysis Patients: Croatian Surveys
Iva Šimunović
; University of Zagreb, University Hospital Center »Sestre Milosrdnice«, Zagreb, Croatia
Draško Pavlović
orcid.org/0000-0002-2380-869X
; University of Zagreb, University Hospital Center »Sestre Milosrdnice«, Zagreb, Croatia
Boris Kudumija
; Dialysis Center Avitum, Zagreb, Croatia
Dubravka Mihaljević
; »J. J. Strossmayer« University, University Hospital Center Osijek, Osijek, Croatia
Vesna Lovčić
; General Hospital Bjelovar, Bjelovar, Croatia
Marko Jakić
; »J. J. Strossmayer« University, University Hospital Center Osijek, Osijek, Croatia
Abstract
Disturbances of bone mineral metabolism are common complications of chronic kidney disease with bone fractures as
one of the most important consequences. The aim of this study was to estimate prevalence of bone fractures among Croatian
hemodialysis patients and to determine the possible fracture risk. The study was carried out in 767 hemodialysis
patients from nine Croatian hemodialysis centers. Demographic, laboratory and bone fracture data were collected from
medical records as well as therapy with vitamin D analogs. Fragility fractures were defi ned according to the World Health
Organization defi nition. In 31 patient a total of 36 fractures were recorded. The prevalence of patients with bone fractures
was 4.0%. The mean age of patients with fractures was 68.6 years. There were 9 male and 22 female patients with fractures.
The mean hemodialysis duration was 63.3 months. Among all fractures the most common were hip fractures (39%)
followed by forearm fractures (22%). This is the fi rst study regarding epidemiology of bone fractures in Croatian hemodialysis
patients. The prevalence of patients with bone fractures in our group of hemodialysis patients is high. Fractures
were more frequent among women and older patients, patients who have been longer on dialysis and in patients with
higher concentration of PTH.
Keywords
hemodialysis; secondary hyperparathyroidism; fragility fractures; epidemiology; Croatia
Hrčak ID:
147691
URI
Publication date:
30.3.2015.
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