Acta clinica Croatica, Vol. 40 No. 4, 2001.
Professional paper
Comparison of Colorectal Cancer Features During Three Periods in Hospital Cancer Registry
Lea Tuzović
Mario Škarica
Dora Brezovečki
Davor Tomas
Žaklina Bedić-Fegeš
Hrvoje Čupić
Dujo Kovačević
Snježana Hrkač-Knežević
Božo Krušlin
Mladen Belicza
Abstract
The aim of the study was to analyze the possible effects of the 1991-1995 war in Croatia on the localization, age and sex distribution and stage of colon cancer. Three periods were analyzed: distant prewar (1982-1983), immediate prewar (1989-1990) and postwar (1998-2000) periods. Patient data were obtained from the computer based colorectal cancer registry established at the Department of Pathology. There was a statistically significant increase in the number of cases with right-sided colon involvement during the postwar period (p<0.01). A shift from the 60-69 to 70-79 age group was observed during the postwar period. There was no statistically significant difference in age and sex distribution of tumors. Concerning TNM staging, patients presented in more advanced stages in the postwar period (p<0.01). A similar difference was also recorded by comparing Dukes’ stages during the three periods of observation (p<0.01). Results of the study pointed to an increasing prevalence of right-sided colon carcinoma. Towards the end of the overall period of observation, patients tended to present in more advanced stages of the disease. These changes could have probably been, at least in part, attributed to the impact of war.
Keywords
Colon, pathology; Colonic neoplasms, epidemiology; Rectal neoplasms, epidemiology; Rectal, pathology; War; Croatia
Hrčak ID:
14881
URI
Publication date:
3.12.2001.
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