Original scientific paper

Amyloid in Acquired Aponeurotic Ptosis

Biljana Kuzmanović

Abstract

PURPOSE: Histopathological and immunohistochemical evaluation of levator aponeurosis in patients with aponeurotic ptosis vs. control aponeurosis obtained from autopsies of cadavers without history of ptosis, especially in relation with presence of amyloid deposition.
MATERIAL AND METHODS: Seven levator specimens were taken from 6 patients, undergoing anterior levator repair due to aponeurotic ptosis. The control group consisted of 12 levator aponeurosis specimens harvested from both lids of 6 cadavers, during autopsy. Congo red was used to detect amyloid and Orcein stain for elastic fibers. Immunohistochemistry was applied as a final marker for amyloid.
RESULTS: In 2 out of 6 (33,3%) aponeurotic patients we demonstrated amyloid. Orbital and systemic involvement was excluded. The levator aponeurosis was attenuated, stretched and grayish in all patients, but still attached to the tarsus. Collagen bundles were thinned with fatty and elastotic degeneration of different grade in all samples. Control group was negative for amyloid.
CONCLUSION: We demonstrated amyloid in 33,3% of patients with aponeurotic ptosis, without systemic amyloidosis, which may open a new perspective in aponeurotic ptosis etiology explanation.

Keywords

Aponeurotic ptosis; Amyloidosis; Aponeurosis histopathology

Hrčak ID:

14993

URI

https://hrcak.srce.hr/14993

Publication date:

1.11.2002.

Article data in other languages: croatian

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