Review article
THE LONG ROAD TO THE USE OF MICROSCOPE IN CLINICAL MEDICINE IN VIVO: FROM EARLY PIONEERING PROPOSALS TO THE MODERN PERSPECTIVES OF OPTICAL BIOPSY
Giovanni Ponti
; Surgical, Medical and Dental Department of Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy
Umberto Muscatello
; Department of Physics, University of Modena and Reggio Emilia, Modena, Italy
Abstract
For a long period the scientists did not recognized the potentialities of the compound microscope in medicine. Only few scientists recognized the potentialities of the microscope for the medicine; among them G. Campani who proposed the utilization of his microscope to investigate the skin lesions directly on the patient. The proposal was illustrated in a letter Acta Eruditorum of 1686. The recent development of optical techniques, capable of providing in-focus images of an object from different planes with high spatial resolution, significantly increased the diagnostic potential of the microscope directly on the patient.
Keywords
clinical use of microscope; Campani’s mocroscope; optical biopsy in vivo
Hrčak ID:
152059
URI
Publication date:
15.12.2015.
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