Original scientific paper

Protective effect of dexetimide and HI-6 in poisoning with highly toxic organophosphorus compounds

K. Wilhelm ; Institute for Medical Research and Occupational Health, University of Zagreb, Zagreb, Croatia
A. Fajdetić ; Institute for Medical Research and Occupational Health, University of Zagreb, Zagreb, Croatia
V. Deljac ; Laboratory of Organic Chemistry, Faculty of Natural Sciences and Mathematics, University of Zagreb, Zagreb
Z. Binenfeld ; Laboratory of Organic Chemistry, Faculty of Natural Sciences and Mathematics, University of Zagreb, Zagreb

Abstract

The protective effect of HI-6 in combination with atropine and dexetimide was compared in mice and rats intoxicated with soman and VX. Both combinations were equally effective. In soman poisoning the relative efficiency both in mice and rats was about 5 while the therapeutic factor in VX poisoning was about 80.

Keywords

Hrčak ID:

161605

URI

https://hrcak.srce.hr/161605

Publication date:

12.9.1979.

Article data in other languages: croatian

Visits: 1.175 *