Meeting abstract
Salivary and Serous Values of Interleukin 6 and Basic Growth Factor of Fibroblasts in Patients with Planocellular Carcinoma
Vanja Vučičević Boras
Nada Čikeš
Josip Lukač
Mišo Virag
Ana Cekić-Arambašin
Abstract
Data can be found in the literature on the roles of interleukin 6 (IL-6) and basic growth factor of fibroblasts (bFGF) in patients with oral carcinomas, although there are no data on salivary IL-6 and bFGF in such patients. The aim of this study was to determine the values of salivary and serum IL-6 and bFGF in 35 patients with planocellular carcinoma of the oral cavity, aged 40 - 73 years (mean age 54 years). A control group consisted of 23 healthy participants, aged 25 years. The data obtained were analysed by Mann-Whitney U test and values of less than 0.001 were considered statistically significant. Serum values IL-6 and bFGF did not significantly differ between the examined and the control group. Increased values of salivary IL-6 and bFGF were determined in the patients with planocellular carcinoma compared with the control group (p<0.001). We can conclude that the increased values of salivary IL-6 and bFGF in patients with planocellular carcinoma originated from local production.
Keywords
Hrčak ID:
1662
URI
Publication date:
15.12.2004.
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