Original scientific paper

Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifolium

LUTFUN NAHAR
WENDY R. RUSSELL
MOIRA MIDDLETON
MOHAMMAD SHOEB
SATYAJIT D. SARKER

Abstract

Reversed-phase preparative HPLC analysis of the methanol extract of the seeds of Ilex aquifolium afforded two antioxidant phenylacetic acid derivatives, 2,4-dihydroxyphenylacetic acid (1) and 2,4-dihydroxyphenylacetic acid methyl ester (2). The structures were determined by spectroscopic methods. In the DPPH assay for antioxidant activity, the IC50 values of 1 and 2 were 1.50 x 10-3 and 2.55 x 10-3 mg mL-1, respectively, compared to 2.88 x 10-5 mg mL-1 of quercetin, a natural antioxidant.

Keywords

Ilex aquifolium (Aquifoliaceae); phenylacetic acid derivatives; antioxidant; DPPH

Hrčak ID:

16756

URI

https://hrcak.srce.hr/16756

Publication date:

1.6.2005.

Article data in other languages: croatian

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