Professional paper
Clonidine for neonatal abstinence syndrome: a single neonatology department’s experience
Darja Paro-Panjan
; Department of Neonatology, Division of Paediatrics University Medical Centre of Ljubljana Bohoriceva 20, 1000 Ljubljana, Slovenia
Abstract
Clonidine has been shown effective in reducing sympathetic hyperactivity in neonatal abstinence syndrome (NAS). The aim of this study was to analyze clinical and laboratory characteristics of a group of newborns treated with clonidine for NAS due to maternal drug addiction and due to withdrawal from opioid analgesic therapy. Only one full–term newborn presented with metabolic acidosis and hyperkalemia; in others no clinical or laboratory adverse effects were detected. This report emphasizes the importance of alertness to potential adverse effects of clonidine therapy, and discusses possible pathophysiological aspects of hyperkalemia and metabolic acidosis during treatment for NAS.
Keywords
newborn; sympathetic hyperactivity; metabolic acidosis; hyperkalemia
Hrčak ID:
170200
URI
Publication date:
1.9.2016.
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