Original scientific paper
Safety of Simultaneous Resections of Colorectal Cancer and Liver Metastases
M. Doko
M. Zovak
M. Ledinsky
A. Mijić
M. Perić
M. Kopljar
R. Čulinović
B. Rode
B. Doko
Abstract
Liver resection is the only potentially curative method for patients with colorectal
cancer metastases and 5-year survival rates are 20% – 40%. Simultaneous resection of
colorectal cancer and synchronous liver metastases has been recommended if minor hepatectomy
is indicated. The purpose of this paper is to analyze the treatment of hepatic
colorectal secondaries and to assess the safety of simultaneous and delayed liver resections
and relations of morbidity to the extensiveness of hepatectomy and perioperative
factors. Analyzed were 21 patients with liver metastases from colorectal cancer operated
between 1997 and 1999 in the Clinical Hospital »Sestre milosrdnice«. Operating time
for simultaneous colorectal and liver resections was not significantly longer compared
to liver resections alone. No significant difference in complication rate was found after
simultaneous procedures and liver resection alone (38% vs. 31%). Complication rate after
major liver resections was not significantly greater than after minor resections (38%
vs. 31%). No statistically significant differences were found in operation time and blood
replacement between patients who developed postoperative complications and those who
did not. In conclusion, simultaneous resections of primary colorectal cancer and liver
metastases may be considered safe. Morbidity rates are not significantly different from
those after liver resections alone, nor depend significantly upon the extensiveness of liver
resection, providing that the operation time and blood loss are within the range observed
in this study.
Keywords
Hrčak ID:
17208
URI
Publication date:
16.12.2000.
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