Skip to the main content

Acta Dermatovenerologica Croatica, Vol. 24 No. 4, 2016.

Other

Assessment of Cardiovascular Risk Factors in Patients with Psoriasis

Olivia Komorowska ; Department of Dermatology, Venerology and Allergology, Medical University of Gdansk
Michal Bohdan ; First Department of Cardiology, Medical University of Gdansk, Poland
Aneta Szczerkowska-Dobosz ; Department of Dermatology, Venerology and Allergology, Medical University of Gdansk
Dorota Rawicz-Zegrzda ; Department of Cardiac Diagnostics, Medical University of Gdansk
Maria Dudziak ; Department of Cardiac Diagnostics, Medical University of Gdansk
Tomasz Zdrojewski ; Department of Preventive Medicine and Education, Medical University of Gdansk
Marcin Gruchala ; First Department of Cardiology, Medical University of Gdansk
Dorota Purzycka-Bohdan ; Department of Dermatology, Venerology and Allergology, Medical University of Gdansk
Roman Nowicki ; Department of Dermatology, Venerology and Allergology, Medical University of Gdansk

Full text: english PDF 156 Kb

page 261-261

downloads: 655

cite

Abstract

Psoriasis is a chronic inflammatory skin disorder associated with increased cardiovascular risk. Aim of this work was to evaluate the association between psoriasis and chosen cardiovascular risk factors, echocardiographic parameters, and carotid intima-media thickness.

A total of 50 patients with psoriasis and 50 controls were enrolled in the study. Psoriasis area severity index was calculated in the study group. Systolic and diastolic blood pressure, body mass index, waist circumference, lipids, fasting glucose, and D-dimer levels were assessed in all patients. In addition, echochardiographic parameters and carotid intima-media thickness were measured.

Patients with psoriasis had higher blood pressure (P=0.001), elevated triglycerides (P=0.0218), lower high-density lipoprotein cholesterol (HDL-C) (P=0.0014), elevated D-dimer levels (p=0.0009), and were more frequently overweight (P=0.0198) in comparison to controls. There were no differences in echocardiographic parameters and carotid intima-media thickness between the psoriasis and control groups. Moreover, a positive correlation between psoriasis area severity index and blood pressure was observed (P=0.0088).

The study confirmed that psoriasis is associated with increased cardiovascular risk. The association between psoriasis, intima-media thickness, and echocardiographic parameters should be evaluated in large prospective studies.

 

Keywords

psoriasis; cardiovascular risk; carotid intima-media thickness

Hrčak ID:

173944

URI

https://hrcak.srce.hr/173944

Publication date:

30.1.2017.

Visits: 1.243 *