Original scientific paper

Clotting changes induced by metal ions in vitro

I. Šimonović ; Department of Medicine, Medical Faculty, University of Zagreb
Krista Kostial ; Institute for Medical Research (incorporating the Institute' of Industrial Hygiene), Zagreb
Anica Maršić ; Institute for Medical Research (incorporating the Institute' of Industrial Hygiene), Zagreb

Abstract

Addition of UO2++, Sr++ and Pb++ to plasma in concentrations from 12,5-62,5 µg/ml does not influence the prothrombin activity. Mercury ions cause a prolongation of the plasma prothrombin time resulting in a reduction of the prothrombin index values to about 55%. This effect of mercury depends on the concentration of mercury ions and the exposure time. The highest reduction in prothrombin index values was observed at concentrations from 25,0-37,5 µg/ml after 3 hours of exposure. At higher or lower concentrations the effect was less pronounced.

Keywords

Hrčak ID:

183009

URI

https://hrcak.srce.hr/183009

Publication date:

14.9.1959.

Article data in other languages: croatian

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