Professional paper

DIAGNOSING MACROAMYLASEMIA IN UNEXPLAINED HYPERAMYLASEMIA

DANIEL VICTOR ŠIMAC ; General Practice, Primorje-Gorski Kotar County Health Centre, Čabar Branch, Čabar, Croatia
MAJA ŠPELIĆ ; Medical Biochemistry Laboratory, Primorje-Gorski Kotar County Health Centre, Delnice Branch, Delnice, Croatia
BOSILJKA DEVČIĆ ; Department of Nephrology, Dialysis and Kidney Transplantation, Rijeka University Hospital Center, Rijeka, Croatia
SANJIN RAČKI ; Department of Nephrology, Dialysis and Kidney Transplantation, Rijeka University Hospital Center, Rijeka, Croatia

Abstract

Macroamylasemia is a curious condition marked by hyperamylasemia without any other signs or symptoms, most frequently caused by immunoglobulin-amylase complexes that cannot be secreted normally by the kidneys. It usually requires no additional investigation, but must be taken into consideration to avoid unnecessary diagnostics and treatment, which burden both the patient and the healthcare system. A number of studies and reports have described macroamylasemia in combination with other conditions or diseases, one of the more interesting being celiac disease, where a gluten free diet was shown to cure both. Our case presents a young female patient without significant signs or symptoms except for elevated serum amylase discovered by chance, and ignored. Macroamylasemia was considered and confirmed, while celiac disease was subsequently excluded.

Keywords

hyperamylasemia; laboratory diagnosis; macroamylasemia

Hrčak ID:

184908

URI

https://hrcak.srce.hr/184908

Publication date:

19.7.2017.

Article data in other languages: croatian

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