Short communication, Note

https://doi.org/10.1515/acph-2017-0038

Influence of plasma on the physical properties of the ointments with quercetin

BEATA SZULC-MUSIOŁ ; Department of Applied Pharmacy, School of Pharmacy and the Division of Laboratory Medicine, Medical University of Silesia, Poland
BARBARA DOLIŃSKA ; Department of Applied Pharmacy, School of Pharmacy and the Division of Laboratory Medicine, Medical University of Silesia, Poland
JUSTYNA KOŁODZIEJSKA ; Department of Applied Pharmacy, Medical University of Łódź, Poland
FLORIAN RYSZKA ; Pharmaceutical Research and Production Plant "Biochefa", Sosnowiec, Poland

Abstract

Effects of two independent variables – the content of quercetin (0 or 1 or 1.5 or 5 %) and the content of plasma (0 or 2 or 4 or 6 %) – on the organoleptic properties and rheological parameters of model formulations prepared on an amphiphilic base were estimated. The consistency of all ointments was uniform, and the content of quercetin and plasma lay within the predefined range. Tested ointments are non-Newtonian systems. The content of quercetin and plasma was found to have a significant effect on the rheological properties of the ointments. An increase in the content of plasma in ointments was accompanied by a significant increase in their hardness, viscosity and shear stress and a reduction of their spreadability. The best rheological properties were shown by formulation F-3, containing 1.5 % of quercetin and 2 % of plasma.

Keywords

quercetin; plasma; ointment; rheological property

Hrčak ID:

186845

URI

https://hrcak.srce.hr/186845

Publication date:

31.12.2017.

Visits: 1.201 *