Original scientific paper

The Molecular Electrostatic Potential as a Determinant of Receptor-Drug Recognition

Dušan Hadži ; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Milan Hodošček ; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Darko Kocjan ; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Tomaž Šolmajer ; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Franc Avbelj ; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia

Abstract

The validity of the concept of the molecular electrostatic .
potential and its applicability in rationalizing drug-receptor interactions
are discussed on hand of examples covering the qualitative
aspects. The computational methods are briefly reviewed with
respect to economy and quality of results.

Keywords

Hrčak ID:

194073

URI

https://hrcak.srce.hr/194073

Publication date:

14.1.1985.

Visits: 756 *