Original scientific paper

https://doi.org/10.2478/v10007-007-0044-2

New synthesized steroidal derivatives using 3betha-hydroxyandrosten-17-one as starting material

NEHAD A. ABD EL-LATIF
MOHAMED M. ABDULLA
ABD EL-GALIL E. AMR

Abstract

In this study, we synthesized some new substituted steroidal derivatives using 3betha-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.

Keywords

dehydroepiandrosterone; steroidal derivatives; androgenic-anabolic agents

Hrčak ID:

19482

URI

https://hrcak.srce.hr/19482

Publication date:

1.3.2008.

Article data in other languages: croatian

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