Acta Pharmaceutica, Vol. 58 No. 1, 2008.
Original scientific paper
https://doi.org/10.2478/v10007-007-0044-2
New synthesized steroidal derivatives using 3betha-hydroxyandrosten-17-one as starting material
NEHAD A. ABD EL-LATIF
MOHAMED M. ABDULLA
ABD EL-GALIL E. AMR
Abstract
In this study, we synthesized some new substituted steroidal derivatives using 3betha-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.
Keywords
dehydroepiandrosterone; steroidal derivatives; androgenic-anabolic agents
Hrčak ID:
19482
URI
Publication date:
1.3.2008.
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