Acta clinica Croatica, Vol. 56. No. 4., 2017.
Original scientific paper
https://doi.org/10.20471/acc.2017.56.04.12
Implementation of Venous Thromboembolism Prophylaxis Guidelines in Clinical Practice: A Retrospective Study in Two Croatian Hospitals
Srećko Marušić
orcid.org/0000-0002-3982-0765
; Department of Clinical Pharmacology, Dubrava University Hospital, University of Zagreb School of Medicine, Zagreb, Croatia
Aleksandar Knežević
; Medical Department, Zadar General Hospital, Zadar, Croatia
Vesna Bačić Vrca
; Department of Clinical Pharmacy, Dubrava University Hospital, Zagreb, Croatia
Ivana Marinović
; Department of Clinical Pharmacy, Dubrava University Hospital, Zagreb, Croatia
Julija Bačić
; Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Paulo Roque Obreli Neto
; Department of Pharmacology and Therapeutics, State University of Maringá, Maringá, PR, Brazil
Daniela Amidžić Klarić
; Department of Clinical Pharmacy, Dubrava University Hospital, Zagreb, Croatia
Dijaneta Diklić
; Medical Department, Zadar General Hospital, Zadar, Croatia
Abstract
The aim of this study was to evaluate the implementation of the 9th edition of the American College of Chest Physicians (ACCP9) guidelines for prevention of venous thromboembolism in nonsurgical patients in clinical practice in one university and one general Croatian hospital. A retrospective study was conducted at Zadar General Hospital from Zadar and Dubrava University Hospital from Zagreb. Medical charts of all patients admitted to Medical Departments in two periods, before and after implementation of the ACCP9 guidelines, were analyzed. The ACCP9 guidelines were made available to all physicians through the hospital electronic information system immediately after the publication. The Hospital Drug Committees promoted implementation of the guidelines during their periodical clinical visits. Overall, 850 patients were included in the study in two periods. There was no statistically significant difference in the number of high-risk patients receiving thromboprophylaxis after the guidelines implementation in either hospital. In both periods, a signifi-cantly higher number of high-risk patients received thromboprophylaxis in Dubrava University Hos-pital in comparison with Zadar General Hospital (31.7% vs. 3.8% and 40.3% vs. 7.3%, respectively; p<0.001). This study revealed insufficient implementation of evidence-based thromboprophylaxis guidelines in clinical practice in two Croatian hospitals.
Keywords
Venous thromboembolism; Practice guidelines as topic; Pharmacy and therapeutics committee; Retrospective studies; Croatia
Hrčak ID:
195433
URI
Publication date:
15.12.2017.
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