Original scientific paper

Syntheses of New Pyrazolo-, and Tetrazolopyridines

M. Laćan ; Laboratory of Organic Chemistry and Technology, Department of Biotechnology, Technological Faculty, University of Zagreb, 41000 Zagreb, Croatia, Yugoslavia
K. Tabaković ; Laboratory of Organic Chemistry and Technology, Department of Biotechnology, Technological Faculty, University of Zagreb, 41000 Zagreb, Croatia, Yugoslavia

Abstract

By the reaction of cyanoacetamide and acetylacetone we
prepared some new pyrazolo(3,4-b) pyridines (8, Sa, 9) and tetrazolo(
l,5-a) pyridines (6, 12, 16) over several reaction steps. Azido-
tetrazolo isomerisation of tetrazolo (l,5-a) pyridines (6, 12, 16) has
been investigated on the basis of their i. r. and n. m. r. spectra in
three solvents (dimethyl sulfokside, chloroform and trifluoroacetic
acid). Compound 8 can be detected as a tetrazolo tautomer in the
solid state as well as in solutions. Compound 16 in the solid state
exists only in the tetrazolo form, while in solutions it exists in both
forms. Compound 12 in the solid state exists only in the azido form,
while in solutions it exists in both forms.

Keywords

Hrčak ID:

196669

URI

https://hrcak.srce.hr/196669

Publication date:

15.10.1975.

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