Original scientific paper

4,5,6, 7-Tetrahydroindazol-3-one Carboxylic Acids. IV. Acid Dissociation Constants and Complex Formation with Calcium, Strontium and Barium

V. Škarić ; Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
V. Turjak-Zebić ; Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
M. Branica ; Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
Đ. Škarić ; Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia

Abstract

The dissociation constants of 2-phenyl-4,5,6,7-tetrahydroindazol-
3-one-5,5-dicarboxylic acid (I, FIDA) and its stability constants
with alkal.ine earth ions are reported. FIDA was first tested for
toxicity by the »Up-and down« method.
In connection with the determination and the interpretation
of pK values of tetrahydroindazolone carboxy1ic acids and their
ethyl esters I - VII the potentiometric titration procedure is
described. The same procedure and apparatus were used for the
potentiometric titration in the presence of metals.
FIDA w as shown to be an excelient reagent for the separation
of barium from strontium.

Keywords

Hrčak ID:

208294

URI

https://hrcak.srce.hr/208294

Publication date:

27.2.1965.

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