Original scientific paper

Secondary a-Deuterium Isotope Effects in the Reaction of 2-Phenylethyltrimethylammonium Ion by Hydroxide Ion in Aqueous Solution and by Ethoxide Ion in Ethanol

S. Ašperger ; Department of Physical Chemistry, Institute »Ruder Boskovic«, Zagreb, and Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia, Yugoslavia
L. Klasinc ; Department of Physical Chemistry, Institute »Ruder Boskovic«, Zagreb, and Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia, Yugoslavia
D. Pavlović ; Department of Physical Chemistry, Institute »Ruder Boskovic«, Zagreb, and Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia, Yugoslavia

Abstract

Secondary a-deuterium isotope effects in the reaction of
2-phenylethyltrimethylammonium iodide with hydroxide ion in
aqueous solution at 97.0° and with ethoxide ion in ethanol at 40.0°
have been found to be very small. The results .suggest that the
hydrogen compound reacts slightly faster than the deuterium
compound. The secondary a-deuterium isotope effect in the reaction
of 2-phenylethyl bromide with sodium ethoxide in ethanol is
appreciably larger and ammounts to 9 per cent per deuterium
atom at 59.8°. The mechanistic implications of these results are
discussed.

Keywords

Hrčak ID:

208304

URI

https://hrcak.srce.hr/208304

Publication date:

30.12.1964.

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