Original scientific paper

Synthetic Studies in the Sulphonamide Series. II. Application of the Wolff Rearrangement to the Preparation of N-Acylsulphonamides

A. Markovac-Prpić ; Research Department, »Pliva« Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia
N. Tipić ; Research Department, »Pliva« Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia

Abstract

The Wolff rearrarigement of a-diazoketones was performed
in the presence of sodium sulphonamides and the corresponding
N-acylsulphonamides were obtained. When tested on rats, these
compounds showed a very strong diuretic activity.

Keywords

Hrčak ID:

208324

URI

https://hrcak.srce.hr/208324

Publication date:

28.2.1964.

Visits: 659 *