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Original scientific paper

Substances Acting on the Central Nervous System. I. Derivatives of N-Acyl-2-phenylbutyramide

S. Kukolja ; Research Department, »Pliva« Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia
Lj. Polak ; Research Department, »Pliva« Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia


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Abstract

In search of compounds which may have hypnotic a!Ild sedative as well as anticonvulsant activi1ties, the N-a cyl-2-phenylbutyramides (X-XIVb) h ave been prepared. These sub.stances have been synthesized by trea ting the alkyl N-acyl iminoes.te r s with hydrochloric acid and the latter (X-XVaY by cond ensation of the iminoesters with appropriaite acyl chlorides.

Keywords

Hrčak ID:

208619

URI

https://hrcak.srce.hr/208619

Publication date:

9.4.1960.

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