Acta clinica Croatica, Vol. 57. No. 3., 2018.
Other
https://doi.org/10.20471/acc.2018.57.03.21
Primary Epithelioid Hemangioendothelioma in the Cerebellum: Case Report with Reference to Drastic Change in the WHO Classification
Ibrahim Omerhodžić
orcid.org/0000-0001-5143-8801
; Department of Neurosurgery, University Clinical Center of Sarajevo, Sarajevo, Bosnia-Herzegovina
Nurija Bilalović
; Department of Clinical Pathology and Cytology, University Clinical Center of Sarajevo, Sarajevo, Bosnia-Herzegovina
Bekir Rovčanin
orcid.org/0000-0002-7298-3240
; School of Medicine, University of Sarajevo, Sarajevo, Bosnia-Herzegovina
Bilal Imširović
; Department of Radiology, Sarajevo General Hospital, Sarajevo, Bosnia-Herzegovina
Enra Suljić
; Department of Neurology, University Clinical Center of Sarajevo, Sarajevo, Bosnia-Herzegovina
Ante Rotim
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Kenan Arnautović
; Semmes-Murphey Clinic and University of Tennessee, Memphis, TN, USA
Abstract
Epithelioid hemangioendothelioma is a rare vascular brain tumor. It develops from endothelial cells, usually in the liver, lung, bone and soft tissue. Primary localization of this tumor in the intracranial space is very uncommon; only 47 cases have been described in the literature. This tumor was initially classified as grade I (benign) in the World Health Organization (WHO) 2007 classification. In 2016, this tumor was re-classified as grade III (malignant). Herein, the first case report of epithelioid hemangioendothelioma in the cerebellum of a male patient is presented. Complete surgical excision was done. No adjuvant therapy was administered. Magnetic resonance imaging performed 2 years after the surgery continued to show no recurrence of the tumor. To our knowledge, this is the first report of cerebellar location of this rare tumor. In addition, the authors report drastic re-classification of the epithelioid hemangioendothelioma from the benign tumor (WHO 2007) to a malignant one (2016), which significantly changes postoperative management and follow up of this brain neoplasm.
Keywords
Hemangioendothelioma, epithelioid; Brain neoplasms; World Health Organization; Cerebellum
Hrčak ID:
216167
URI
Publication date:
1.9.2018.
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