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Recurrent invasive meningococcal disease in a patient with complement deficiency: a case report
Vedran Stevanović
orcid.org/0000-0002-8456-6276
; Pediatric Infectious Diseases Department, University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Branko Miše
; Pediatric Infectious Diseases Department, University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Abstract
Most cases of invasive meningococcal disease occur in immunocompetent children and young adults. Serogroup B accounts for most cases in Europe followed by serogroup C, while serogroups Wand Y are uncommon. We describe a case of recurrent invasive meningococcal disease (IMD) caused by two different serogroups in a 16-year-old boy with complement deficiency. All tested cultures were negative, but PCR from blood was positive in both episodes. Our patient gradually recovered without sequelae. This case report emphasizes also the need to provide appropriate chemoprohylaxis and/or immunoprophylaxis to certain individuals.
Keywords
recurrent invasive meningococcal disease; polymerase chain reaction (PCR); chemoprohylaxis; immunoprophylaxis
Hrčak ID:
216303
URI
Publication date:
28.1.2019.
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