Review article

https://doi.org/10.20471/LO.2018.46.02-03.15

Optimal treatment of patients with high-risk prostate cancer

Katarina Antunac orcid.org/0000-0002-8356-9897 ; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Abstract

Treatment options in subset of patients with high-risk prostate cancer are various: radical prostatectomy, hormonal therapy, radiation therapy, combined modality approach, addition of chemotherapy. Based on randomised trials data, optimal approach would consist of radical radiotherapy and long term hormonal therapy. If technically possible high dose radiotherapy, hypofractionation, image guided radiotherapy, simultaneous integrated boost on dominant intraprostatic lesion and HDR brachytherapy boost should be used as well.

Keywords

high risk prostate cancer; radiotherapy; hormonal therapy; dose escalation; hypofractionation; simultaneous integrated boost

Hrčak ID:

217800

URI

https://hrcak.srce.hr/217800

Publication date:

29.1.2019.

Article data in other languages: croatian

Visits: 1.712 *