Original scientific paper

https://doi.org/10.11613/BM.2019.020702

Impact of an Andean breakfast on biochemistry and immunochemistry laboratory tests: an evaluation on behalf COLABIOCLI WG-PRE-LATAM

Wilson Bajaña orcid.org/0000-0003-4529-7971 ; International Laboratories Services, INTERLAB S.A., Guayaquil, Ecuador
Eduardo Aranda orcid.org/0000-0001-6590-990X ; Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile; Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI),
Maria Elena Arredondo orcid.org/0000-0001-5550-7763 ; BIONET S.A., Santiago, Chile; Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI), Montevideo, Uruguay
Lorena Michele Brennan-Bourdon orcid.org/0000-0003-3361-4765 ; Clinical Laboratory Network from the state of Jalisco, Public Health State Laboratory (LESP), Comisión para la Protección contra Riesgos Sanitarios del Estado de Jalisco (COPRISJAL), Mexico; Latin American Working Group for Preanalytical Phase (WG-PRE-LAT
Marise Danielle Campelo ; Clinical Laboratory Bioanalise, Teresina, Piaui, Brazil
Edgar Espinoza orcid.org/0000-0002-3526-305X ; Servicio de Acreditación Ecuatoriano (SAE), Quito, Ecuador
Silvia Flores orcid.org/0000-0003-4067-5355 ; Universidad Peruana Cayetano Heredia, Lima, Perú; Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI), Montevideo, Uruguay
Patricia Ochoa ; Facultad de Medicina Universidad Católica de Cuenca, Cuenca, Ecuador; Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI), Montevideo, Uruguay
Veronica Vega orcid.org/0000-0002-4659-2609 ; Universidad de Guayaquil, Guayaquil, Ecuador
Beatriz Varela ; LAC, Montevideo, Uruguay;Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI), Montevideo, Uruguay
Gabriel Lima-Oliveira orcid.org/0000-0002-5937-9137 ; Section of Clinical Biochemistry; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; Latin American Working Group for Preanalytical Phase (WG-PRE-LATAM) of the Latin America Confederation of Clinical Bioch

Abstract

Introduction: In Andean countries, specifically in Ecuador, a food transition in the population has been observed because of economic growth. The Working Group for Preanalytical Phase in Latin America (WG-PRE-LATAM) of the Latin America Confederation of Clinical Biochemistry (COLABIOCLI) was established in 2017, and its main purpose is to study preanalytical variability and establish guidelines for preanalytical procedures in order to be implemented by clinical laboratories and healthcare professionals in Latin America. The aim of this study on behalf of COLABIOCLI WG-PRE-LATAM was to evaluate whether an Andean breakfast can interfere with routine biochemistry and immunochemistry laboratory tests.
Materials and methods: We studied 20 healthy volunteers who consumed an Andean breakfast containing a standardized amount of carbohydrates, proteins and lipids. We collected blood specimens for laboratory tests before breakfast and 1, 2, and 4 hours thereafter. Significant differences between samples were assessed by the Wilcoxon ranked-pairs test.
Results: The Andean breakfast statistically (P ≤ 0.05), modified the results of the following tests: triglycerides, insulin, cortisol, thyroid stimulating hormone, free thyroxine, total protein, albumin, urea, creatinine, lactate dehydrogenase, alkaline phosphatase, amylase, lipase, total bilirubin, direct bilirubin, iron, calcium, phosphorus, magnesium, and uric acid.
Conclusions: Andean breakfast can influence the routine biochemistry and immunochemistry laboratory tests and might expose patient safety to some risks. Therefore, the COLABIOCLI WG-PRE-LATAM calls attention and highlights that the fasting time needs to be carefully considered when performing blood testing in order to prevent spurious results and thus, reduce laboratory errors.

Keywords

blood specimen collection; diagnostic errors; fasting; postprandial period; reproducibility of results

Hrčak ID:

218973

URI

https://hrcak.srce.hr/218973

Publication date:

15.6.2019.

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