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Acta Dermatovenerologica Croatica, Vol. 27 No. 1, 2019.

Review article

Face and scalp basal cell carcinoma treatment: A review of the literature

Nicoletta Bernardini ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Nevena Skroza orcid id orcid.org/0000-0003-4478-5404 ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Sara Zuber ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Ersilia Tolino ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Veronica Balduzzi ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Alessandra Mambrin ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Anna Marchesiello ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Alessia Anzalone ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Daniela Colapietra ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Ilaria Proietti ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy
Concetta Potenza ; Dermatology Unit “Daniele Innocenzi”, Dept of Medical-Surgical Sciences and Bio-Technologies, Sapienza University of Rome, Polo Pontino, Italy

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Abstract

Basal cell carcinoma (BCC) is the most frequent skin cancer and is characterized by slow growth, even if it can be locally invasive and rarely metastasizes. Many different phenotypic presentations and histopathologic subtypes have been described, and the current guidelines subdivide BCCs into low-risk (nodular and superficial) and high-risk subtypes (micronodular, infiltrating, and morphoeic BCC and those with squamous differentiation). Dermoscopy allows the identification of the features associated with these different subtypes. Compared with the low-risk forms of BCC, more aggressive ones tend to undergo more frequently incomplete surgical excision and perineural invasion, so the identification of these lesions before surgery is extremely important. The gold standard of treatment is surgery, particularly for the H region of the face and infiltrative lesions, but other options are available and selected according to many variables, including body area, age, comorbidities, and clinical, dermoscopic, and histopathological features of the lesion. Moreover, the possible complications of surgical approaches, namely healing defects, failure of skin grafts, and wound infection, should be considered. In this review we discuss the management of BCC localized on the face and scalp, according to the currently available treatment options.

 

Keywords

Hrčak ID:

219585

URI

https://hrcak.srce.hr/219585

Publication date:

25.4.2019.

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