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Signa vitae : journal for intesive care and emergency medicine, Vol. 15 No. 1, 2019.

Original scientific paper

https://doi.org/10.22514/SV151.042019.9

Role of Redcell Distribution Weight in Predicting Disease Severity, Mortality and Complication in Patients With Acute Pancreatitis

TAHTACI KARAALI REZAN orcid id orcid.org/0000-0003-1831-2566 ; Izmir Katip Celebi University Atatürk Research and Training Hospital Emergency Department, Izmir/TURKEY
TOPAL FIRDEVS
KARAKAYA ZEYNEP
PAYZA UMUT
KAVALCI CEMIL orcid id orcid.org/0000-0003-4201-8850
TOPAL FATIH ESAD

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Abstract

The goal of the present study was to investigate the significance of the Red Cell Distribution Width (RDW) in identifying the severity, mortality and complications of the disease at an early stage in patients with acute pancreatitis (AP).

343 patients with AP presented to the emergency department during one year were included in this retrospective study. Demographic, laboratory and imaging results were recorded. Bedside Index for Severity in AP (BISAP) score was calculated. The patients who developed pancreatitis-related mortality were recorded.

The diagnostic powers of RDW values in the diagnosis of BISAP Score (≥3), exitus, severe pancreatitis and pancreatitis with complication were analysed by means of Receiver Operating Characteristic Curve (ROC) analysis. p<0,05 was considered statistically significant.

The mean age of the subjects was 59,7 ± 18,0 years. Area under curve (AUC) in ROC analysis conducted for RDW in patients with BISAP score≥ 3 was 0,649 (95% Cl 0,576-0,722) and p <0,001. For developed complications, AUC for RDW was 0,558 (95% Cl 0,454-0,662) and p was 0,243. For RDW<14,4 cut-off value; the sensitivity was 66,25%, specificity was 71,48% in the prediction of BISAP≥ 3, sensitivity was 87,5%, specificity was 65,14% in the prediction of mortality, sensitivity was 72,73%, specificity was 71,12% in the prediction of severe AP.

RDW is as significant as the BISAP score in predicting the severity and mortality of pancreatitis in the patients with acute pancreatitis in the emergency department(ED). But it cannot predict the complications in AP.

Keywords

Emergency; acute pancreatitis; mortality; severity; complications; redcell distribution weight

Hrčak ID:

219767

URI

https://hrcak.srce.hr/219767

Publication date:

1.5.2019.

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