Acta clinica Croatica, Vol. 58. No. 1., 2019.
Other
https://doi.org/10.20471/acc.2019.58.01.22
Successful Treatment of Acute Disseminated Encephalomyelitis (ADEM) by Prompt Usage of Immunoglobulins – Case Report and Review of the Literature
Ana Repić-Buličić
; Department of Neurology, Split University Hospital Centre, Split, Croatia
Petar Filipović-Grčić
; Department of Neurology, Split University Hospital Centre, Split, Croatia
Eni Jadrijević
; Department of Neurology, Split University Hospital Centre, Split, Croatia
Pavao Jurinović
; Department of Neurology, Split University Hospital Centre, Split, Croatia
Marina Titlić
; Department of Neurology, Split University Hospital Centre, Split, Croatia
Abstract
Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system that usually affects children and young adults. It most commonly has a monophasic course, although relapses are reported. Clinical presentation of the disease
includes encephalopathy and multifocal neurological deficits. There are no established reliable criteria for diagnosis of ADEM and sometimes it is difficult to distinguish it from first attack of multiple sclerosis, especially in adults. The diagnosis of ADEM is based on clinical, radiological and laboratory findings. In the treatment of ADEM, high doses of corticosteroids, plasmapheresis and immunoglobulins are used. We report a case of a young adult female patient with ADEM who fully recovered after prompt administration of high dose methylprednisolone and immunoglobulins.
Keywords
Encephalomyelitis, acute disseminated; Immunoglobulins; Adrenal cortex hormones; Methylprednisolone; Case reports
Hrčak ID:
220915
URI
Publication date:
1.3.2019.
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