Review article

Association between acute phase response, oxidative status and mastitis in cows

Miroslaw Kleczkowski ; Faculty of Veterinary Medicine Warsaw University of Life Sciences, Warsaw, Poland;
Wlodzimierz Kluciński ; Faculty of Veterinary Medicine Warsaw University of Life Sciences, Warsaw, Poland;
Marian Czerski ; District Veterinary Office in Łomża, Łomża, Poland
Emilian Kudyba ; District Veterinary Office in Łomża, Łomża, Poland

Abstract

There are many studies exploring the topic of acute phase response and oxidative status in inflammationofthemammaryglandofcows. However, many phenomena are relatively poorly understood. Mastitis is associated with significantly higher concentrations of inflammatory and oxidative mediators in the cells and blood. Results of experiments have shown that there are evident changes in serum interleukins (IL), acidglycoprotein (alpha1AG), tumour necrosis factor (TNF), and haptoglobin (Hp). Thus, local and systemic inflammation might play important roles in increased mammary oxidative stress. Reactive oxygen species (ROS) have been implicated in the pathogenesis of a variety of diseases, including mastitis and in transgenic technology leading to the production of new bacterial proteins, which is very important in the prevention of mastitis. An interaction has also been observed between inflammatory and oxidative mediators. These results suggest an important role played by the acute phase response and oxidative status in inflammation of the mammary gland.

Keywords

acute phase response; oxidative status; mastitis; cow

Hrčak ID:

222055

URI

https://hrcak.srce.hr/222055

Publication date:

11.6.2017.

Article data in other languages: croatian

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