Skip to the main content

Technologica Acta : Scientific/professional journal of chemistry and technology, Vol. 12 No. 1, 2019.

Original scientific paper

https://doi.org/10.5281/zenodo.3268784

Synthesis, spectral characterization, antibacterial and antifungal activity of copper(II)-pABA Complex

Emir Horozić orcid id orcid.org/0000-0003-0242-3093 ; Faculty of Technology, University of Tuzla, Univerzitetska 8, 75000 Tuzla, Bosnia and Herzegovina
Zahida Ademović orcid id orcid.org/0000-0002-3780-1608 ; Faculty of Technology, University of Tuzla, Univerzitetska 8, 75000 Tuzla, Bosnia and Herzegovina
Jasmin Suljagić ; Faculty of Technology, University of Tuzla, Univerzitetska 8, 75000 Tuzla, Bosnia and Herzegovina
Amira Cipurković ; Faculty of Natural Sciences and Mathematics, University of Tuzla, Univerzitetska 4, 75000 Tuzla, Bosnia and Herzegovina
Enida Roša ; Faculty of Pharmacy, University of Tuzla, Univerzitetska 8, 75000 Tuzla, Bosnia and Herzegovina
Adisa Sejfić ; Faculty of Pharmacy, University of Tuzla, Univerzitetska 8, 75000 Tuzla, Bosnia and Herzegovina
Darja Husejnagić ; Faculty of Natural Sciences and Mathematics, University of Tuzla, Univerzitetska 4, 75000 Tuzla, Bosnia and Herzegovina
Snježana Hodžić ; Faculty of Natural Sciences and Mathematics, University of Tuzla, Univerzitetska 4, 75000 Tuzla, Bosnia and Herzegovina

Full text: english pdf 517 Kb

page 27-30

downloads: 397

cite

Abstract

pABA (p-aminobenzoic acid or 4-aminobenzoic acid) is a chemical component of the folate molecule produced by plants and bacteria, and found in many foods. It is best known as a UV-blocking sunscreen applied to the skin, and is sometimes taken orally for certain medical conditions. Today it is known that many organic molecules in the human body can react with biometals such as copper, cobalt, manganese, iron and others. This study was performed to investigate the interaction of Cu(II) ions with p-aminobenzoic acid. Spectroscopic methods (FTIR and UV/Vis spectroscopy) were used to characterize the product obtained. The antimicrobial activity of the synthesized complex was tested by diffusion techniques. The results of spectroscopic analysis indicate the interaction of Cu(II) ions with pABA. Interaction is realized through oxygen donor atom of ligand. It was found that the Cu(II) complex has significant antimicrobial activity compared to the pABA ligand.

Keywords

p-aminobenzoic acid; copper; FTIR; UV/Vis; antimicrobial analysis

Hrčak ID:

222403

URI

https://hrcak.srce.hr/222403

Publication date:

5.7.2019.

Visits: 1.125 *