Acta clinica Croatica, Vol. 58. No. 2., 2019.
Other
https://doi.org/10.20471/acc.2019.58.02.25
Burkitt Lymphoma in Gastrointestinal Tract: a Report of Two Cases
Aleksandar Čubranić
Marin Golčić
Dora Fučkar-Čupić
Boris Brozović
Domagoj Gajski
Ivan Brumini
Abstract
Burkitt lymphoma, a type of non-Hodgkin B-cell lymphoma, is the fastest growing human cancer, presenting pathologically with a ‘starry sky’ pattern. It is most often found in the abdomen and the jaw, however, localization in the abdomen other than the ileocecal area is very rare and described only in a handful of cases. Standard treatment consists of initial tumor cytoreduction followed by intense chemotherapy. Most of the relapses occur within one year of the diagnosis, while the 5-year survival is around 80%. We present two cases which are specific for unusual location of Burkitt lymphoma in the colon and stomach, in immunocompetent patients with negative Epstein-Barr virus tests. Also, one of the patients presented is one of the oldest ever reported with abdominal Burkitt lymphoma, while the other patient is an example of diagnostic difficulties in distinguishing
Burkitt lymphoma from similar lymphomas. Due to the rapidly growing tumors and urgent need for cytoreductive surgery, it is crucial to consider the diagnosis of Burkitt lymphoma even in atypical localizations
or absence of the common risk factors associated with Burkitt lymphoma.
Keywords
Burkitt lymphoma; Case reports; Colon; Cytoreduction surgical procedures
Hrčak ID:
224615
URI
Publication date:
1.6.2019.
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