Original scientific paper
Guillain-Barre Syndrome in Patients with Seroconversion of IgG Antibodies to Borrelia Burgdorferi sensu lato
Anđelko Vrca
Ljiljana Mišić-Majerus
Roman Poje
Nada Sikić
Eva Ružić-Sabljić
Vesna Bačić-Vrca
Marina Titlić
Ante Punda
Abstract
A case of polyneuroradiculitis (Guillain-Barre Syndrome) is presented, which was diagnosed in a 62 year-old man after
progressive weakness in the legs and arms and double vision, preceded by severe pain in the back. Diagnosis was
made on the basis of electromioneurography, a specific finding of cerebrospinal fluid (albumino-citological dissociation),
and the clinical course of the disease. Serological analysis of serum included Borellia Burgdorferi sensu lato (BBSL).
Positive findings (slowing of conduction velocity of sensor and motor neurones, and marked albumino-citological dissociation),
together with the dynamics of these findings on the 33rd, 67th and 101st days and one year and a half after the
first clinical signs of disease, indicated the possibility of BBSL infection. Because of the absence of clear clinical and
serological signs of other infections it was assumed that BBSL might be the possible trigger for Guillain-Barre Syndrome.
The fact that there were no obvious clinical signs of infection with BBSL, only serological, suggests that in the
case of unclear aetiology of Guillain-Barre Syndrome BBSL should not be excluded.
Keywords
Guillain-Barre Syndrome; neuroborelliosis; Borellia Burgdorferi
Hrčak ID:
22721
URI
Publication date:
8.5.2008.
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