Original scientific paper
https://doi.org/10.20471/LO.2019.47.02-03.08
The difference between left and right colon cancer patients’ characteristics - single center experience
Darko Kotromanović
orcid.org/0000-0001-9594-4650
; Department of Otorhinolaryngology and Plastic Surgery of the Head and Neck, University Hospital Center Osijek, Osijek, Croatia
Zdenka Kotromanović
; Institute of Oncology, University Hospital Center Osijek, Osijek, Croatia
Ilijan Tomaš
; Department of Otorhinolaryngology and Plastic Surgery of the Head and Neck, University Hospital Center Osijek, Osijek, Croatia
Josipa Flam
; Department of Otorhinolaryngology and Plastic Surgery of the Head and Neck, University Hospital Center Osijek, Osijek, Croatia
Sonja Kotromanović
; Department of Anesthesiology, Reanimatology and Intensive Care, University Hospital Dubrava, Zagreb, Croatia;
Željko Kotromanović
; School of Medicine, Osijek, Croatia
Mirela Penc-Šambić
; Institute of Oncology, University Hospital Center Osijek, Osijek, Croatia
Abstract
Objectives: The purpose of the study was to determine the difference in time until the appearance of relapse or metastases in patients treated for colorectal cancer, depending on the location of the tumor in the left or right colon at the Oncology Clinic of Clinical Medical Centre Osijek between 1st January 2010 and 31st December 2012.
Study design: historical prospective study
Material and methods: Study included patients whose data were recorded from medical archive at the Oncology Clinic of Clinical Medical Centre Osijek. The data on patients’ deaths were recorded from the Registry Office of the Republic of Croatia.
Results: The study included 272 patients, 160 (58.8%) men and 112 (41.2%) women. According to the location, left sided colon tumor was discovered in 211 (77.6%) patients and right-sided in 61 (22.4%). The median age was 67 years. Right-sided colon tumors are considerably larger with median diameter of 6 cm, with median number of 16. Median of time until the appearance of the metastases is 20 months (interquartile range is from 8 to 29 months); marked time being shorter in right-sided colon tumors. Positive outcome of the treatment was achieved in 205 (75.4%) patients, with no significant difference in comparison to the colon cancer localization. By using Kaplan-Meier analysis of patients’ survival rates, a total 5- year survival rate of 72% was achieved in right-sided colon tumor in comparison to 62% in patients with the left-sided colon tumor.
Conclusion: This study confirms that there is a difference in colorectal cancer according to its localisation. Patients with right-sided colorectal cancer are older, the carcinoma is larger, the time until the appearance of a relapse or a metastases is shorter in right sided colon cancer while 5-year survival rate is lower in left sided colon cancer.
Keywords
colorectal cancer; oncology; colon
Hrčak ID:
233606
URI
Publication date:
28.1.2020.
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