Original scientific paper

https://doi.org/10.46419/vs.51.6.7

Duration of immunity acquired by vaccination with the live attenuated vaccine Avishield IB H120 against infectious bronchitis virus in SPF chickens

Lana Ljuma Skupnjak orcid.org/0000-0003-0039-9712 ; Genera Inc. (u sastavu Dechra Pharmaceuticals PLC), Rakov Potok, Hrvatska
Anto Vrdoljak orcid.org/0000-0001-5236-3514 ; Genera Inc. (u sastavu Dechra Pharmaceuticals PLC), Rakov Potok, Hrvatska
Nikol Očuršćak ; Genera Inc. (u sastavu Dechra Pharmaceuticals PLC), Rakov Potok, Hrvatska

Abstract

The most effective means of controlling infectious bronchitis in poultry is by vaccination. Live attenuated vaccines based on the H120 strain (Mass serotype) are the most commonly used vaccines. Since vaccination is often performed in the hatchery, long duration of immunity is preferred. Avishield IB H120, a live attenuated vaccine based on the strain H120 is registered across the European Union and other countries, and has a declared immunity period of up to 5 weeks after vaccination. This study presents the results of an additional survey demonstrating protection against challenge with the IBV strain M41 up to 8 weeks after a single vaccination with Avishield IB H120. Seven weeks after vaccination, 94% of chickens vaccinated by spray were protected against the challenge. Eight weeks after vaccination, 80% of spray vaccinated chickens and 75% of orally vaccinated chickens were still protected against the challenge with virulent IBV.

Keywords

infectious bronchitis virus; vaccination; duration of immunity

Hrčak ID:

239855

URI

https://hrcak.srce.hr/239855

Publication date:

1.10.2020.

Article data in other languages: croatian

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