Case report
https://doi.org/10.5671/ca.44.1.6
Prognostic Significance of Alkaline Phosphatase Activity and Callus Volume in Operatively Treated Bone Fractures
Ante Muljačić
; Department of Traumatology, Sisters of Charity Hospital Center Zagreb, Croatia
Renata Poljak-Guberina
; Department of Dental Prosthetics, School of Medicine, University of Split, Croatia
Ognjen Živković
; Institute for Rehabilitation and Orthopedic Assistance, Clinical Hospital Center Zagreb, Croatia
Marko Guberina
; Department of Oral Surgery, Dental Clinic Zagreb, Croatia
Matea Majstorović-Matejić
; Department of Dental Prosthetics, School of Medicine, University of Split, Croatia
Abstract
Total and bone alkaline phosphatase are indicators of bone formation, a process essential in bone healing. The aim of this study was to assess the relationship of both total and bone alkaline phosphatase with the course and features of healing in surgically treated long bone fractures as compared to the callus volume. In this study, total and bone alkaline phosphatase levels and the callus volume were measured in two patients with long bone fractures. Fracture healing was rapid in one patient and slow in the other. Depending on the healing outcome, on day 7 an increase in the case of slow healing and a decrease in the case of rapid healing was noted for both total and bone alkaline phosphatase. In the case of slow healing, the callus volume was significant whereas in the case of rapid healing the callus was almost invisible on day 7. This result indicates a possible prognostic significance of aforementioned clinical biochemical and radiographic parameters in the monitoring of long bone fracture healing.
Keywords
alkaline phosphatase, callus volume, long bone fracture
Hrčak ID:
240046
URI
Publication date:
10.4.2020.
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