Original scientific paper
https://doi.org/10.5599/jese.774
Polymethionine modified carbon nanotube sensor for sensitive and selective determination of L-tryptophan
Nambudumada S. Prinith
; Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constituent College, Karnataka, India
Jamballi G. Manjunatha
orcid.org/0000-0002-0393-2474
; Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constituent College, Karnataka, India
Abstract
The electrochemically initiated catalytic oxidation of amino acid L-tryptophan (L-TPN) in phosphate buffer solution has been scrutinized using highly conductive polymethionine modified carbon nanotube paste sensor (PMETCNTPS) through cyclic voltammetry (CV) technique. Compared to the bare carbon nanotube paste sensor (BCNTPS), PMETCNTPS exhibited a quantifiable current signal by CV method. PMETCNTPS was found sensitive to L-TPN concentrations within the linear segment of detection range 1.5 - 8.0×10-5 M. By employing the calibration plot, the detection limit was determined as 6.99×10-7 M. In addition, PMETCNTPS was successfully exploited and validated in determining L-TPN in the pharmaceutical supplement.
Keywords
Electrochemical sensor; tryptophan; electropolymerization; cyclic voltammetry
Hrčak ID:
242256
URI
Publication date:
29.7.2020.
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