Review article

https://doi.org/10.11613/BM.2020.030501

Laboratory testing of extravascular body fluids: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Part II – Synovial fluid

Anja Jokic orcid.org/0000-0003-3505-5178 ; Croatian Society of Medical Biochemistry and Laboratory Medicine, Working group for extravascular body fluid samples; Department of Medical Biochemistry, Haematology and Coagulation with Cytology, University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
Lara Milevoj Kopcinovic orcid.org/0000-0003-0360-9148 ; Croatian Society of Medical Biochemistry and Laboratory Medicine, Working group for extravascular body fluid samples; Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Jelena Culej ; Croatian Society of Medical Biochemistry and Laboratory Medicine, Working group for extravascular body fluid samples; Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Irena Kocijan ; Croatian Society of Medical Biochemistry and Laboratory Medicine, Working group for extravascular body fluid samples; Medical Biochemistry Laboratory, General hospital Varaždin, Varaždin, Croatia
Marija Bozovic ; Croatian Society of Medical Biochemistry and Laboratory Medicine, Working group for extravascular body fluid samples; Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Abstract

Joint diseases are conditions with an often progressive and generally painful nature affecting the patient’s quality of life and, in some cases, requiring
a prompt diagnosis in order to start the treatment urgently. Synovial fluid (SF) laboratory testing is an important part of a diagnostic evaluation
of patients with joint diseases. Laboratory testing of SF can provide valuable information in establishing the diagnosis, be a part of a patient’s
follow-up and treatment with the purpose of improving the patient’s health and quality of life.
Synovial fluid laboratory testing is rarely performed in Croatian medical biochemistry laboratories. Consequently, procedures for SF laboratory testing
are poorly harmonized. This document is the second in the series of recommendations prepared by the members of the Working group for
extravascular body fluid samples of the Croatian Society of Medical Biochemistry and Laboratory Medicine. It addresses preanalytical, analytical,
and postanalytical issues and the clinical significance of tests used in SF laboratory testing with the aim of improving the value of SF laboratory testing
in the diagnosis of joint diseases and assisting in the achievement of national harmonization. It is intended for laboratory professionals and all
medical personnel involved in synovial fluid collection and testing.

Keywords

recommendations; synovial fluid; crystal analysis; osteoarthritis; gout

Hrčak ID:

244718

URI

https://hrcak.srce.hr/244718

Publication date:

15.10.2020.

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