Original scientific paper

On the Reaction of Diphthaloyl-DL-lysine Chloride with Dibenzyl Sodiomethylmalonate. Preparation of DL-4,8-Diamino-3-octanone

N. Ž. Stanaćev ; Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia
M. Proštenik ; Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia

Abstract

The applicability of the Bowman ketone synthesis to diamino acids has been demonstrated. Thus, diphthaloyl-DL-lysine chloride (III) was condensed with dibenzyl sodiomethylmalonate yielding DL-4,8-diphthalimido-3-octanone (V). The latter gave by hydrolysis DL-4 ,8-diamino-3-octanone (VI).

Keywords

Hrčak ID:

246834

URI

https://hrcak.srce.hr/246834

Publication date:

6.2.1957.

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