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Acta clinica Croatica, Vol. 59. No. Supplement 1, 2020.

Original scientific paper

Autologous Fat Augmentation in The Treatment of Unilateral Vocal Fold Paralysis – A 15-Year Experience in a Single Institution

Ratko Prstačić orcid id orcid.org/0000-0003-3623-3562 ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia; Faculty of Education and Rehabilitation Sciences, Zagreb University, Croatia
Juraj Slipac orcid id orcid.org/0000-0001-8475-8289 ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia
Tamara Živković Ivanović ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia
Ivana Šimić orcid id orcid.org/0000-0002-7150-6645 ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia
Ema Babić ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia
Ana Đanić Hadžibegović orcid id orcid.org/0000-0001-8513-5032 ; ENT Department, University Hospital Centre Zagreb, Zagreb, Croatia; Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Croatia; School of Medicine, Zagreb University, Croatia

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Abstract

Autologous fat vocal fold augmentation is a widespread surgical procedure that
aims to repair glottal incompetence in patients with unilateral vocal fold paralysis (UVFP). However,
there are some concerns in the literature about the long-term results of this technique. At the ENT
Department of the Zagreb University Hospital Centre, this technique has been in use for more than
15 years, and a retrospective medical chart review was conducted from June 2005 to November 2019.
Overall, 78 patients with UVFP met the inclusion criteria for enrolment in the study. All patients
underwent at least one preoperative and two postoperative voice assessments, one early (within 3
months from surgery) and one late (at least 1 year after surgery). All tested voice outcome parameters
(maximum phonation time (MPT), jitter, shimmer, noise-to-harmonic ratio (NHR )) significantly
improved after surgery, both early and late postoperatively (p<0.001). The reoperation rate was only
10.3% (8/78), with the majority of patients in our series experiencing long-term benefits from this
surgical procedure. According to the results of our study, autologous fat vocal fold augmentation appears
to be a highly useful and effective surgical technique with long-lasting results in the majority of
patients suffering from UVFP.

Keywords

autologous fat; augmentation; vocal fold paralysis

Hrčak ID:

247895

URI

https://hrcak.srce.hr/247895

Publication date:

1.11.2020.

Article data in other languages: croatian

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