Croatica Chemica Acta, Vol. 93 No. 2, 2020.
Original scientific paper
https://doi.org/10.5562/cca3700
Synthesis and Biological Assessment of Carbazole Linked Pyrazole Schiff bases and Diarylthiourea Derivatives
Gopinath D. Shirole
; Department of Chemistry, A. S. C. College Rahata, Ahmednagar, MS 423107, India
Gajanan R. Pandhare
; Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, MS, 413713, India
Anil G. Gadhave
; Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, MS, 413713, India
Bhagawat K. Uphade
; Padmashri Vikhe Patil College of Arts, Science and Commerce, Pravaranagar, MS, 413713, India
Dilip S. Aute
; Department of Chemistry, A. C. S. College Satral, Rahuri, Ahmednagar, MS 413711, India
Vijay A. Kadnor
; Department of Chemistry, A. C. S. College Satral, Rahuri, Ahmednagar, MS 413711, India
Abstract
In this study, (E)-9-ethyl-N-((1,3-diphenyl-1H-pyrazol-4-ylmethylene)-9H-carbazol-3-amine (3a–f) and 1-(9-ethyl-9H-carbazol-6-yl)-3-phenylthiourea (5a–f) derivatives were synthesized and their in vitro antimicrobial and antimalarial activities were evaluated. The structures of the synthesized compounds were elucidated and confirmed by using IR, 1H NMR, 13C NMR, and mass spectra.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords
antimicrobial; antimalarial activities; carbazole; diarylthiourea; Schiff base
Hrčak ID:
251398
URI
Publication date:
11.10.2020.
Visits: 1.160 *