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https://doi.org/10.20471/LO.2021.49.01.06
Uterine choriocarcinoma - a case report
Vanda Paradžik-Pašalić
orcid.org/0000-0002-8849-9322
; Department of Gynecological Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Joško Lešin
; Department of Gynecological Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Višnja Matković
; Department of Gynecological Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Suzana Lide-Škalec
; Department of Gynecological Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Abstract
Choriocarcinoma is one of the histological types of entities called gestational trophoblastic neoplasia (GTN) that refers to a rare group of malignancies that are formed by abnormal proliferation of trophoblastic tissue. Choriocarcinoma is the most aggressive GTN histological type and is characterized by early vascular invasion and disseminated disease. The clinical presentation depends on the spread of the disease and the location of the seedlings. In this paper we present the case of a 32-year-old patient sent to our Department for a specific oncological treatment of uterine choriocarcinoma diagnosed in an external institution. The disease is according to FIGO and WHO scale classified as III stage, low risk and chemotherapy with methotrexate and folic acid is indicated. The chemotherapy achieved negativity of the initially elevated tumor marker human chorionic gonadotropin (hCG) and full regression of lesions described in computerized tomography (CT).
Keywords
gestational trophoblastic neoplasia; choriocarcinoma; FIGO and WHO Classification; hCG; methotrexate
Hrčak ID:
257766
URI
Publication date:
25.5.2021.
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