Conference paper
ANXIETY AND DEPRESSION IN PATIENTS WITH ACUTE LEUKAEMIA TREATED WITH HEMATOPOIETIC STEM CELL TRANSPLANTATION
Anna Warchala
; Department of Psychiatry Rehabilitation, Medical School of Silesia, Katowice, Poland ;Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Irena Krupka-Matuszczyk
; High Medical School of Silesia, Katowice, Poland
Krzysztof Krysta Krysta
; Department of Psychiatry Rehabilitation, Medical School of Silesia, Katowice, Poland
Abstract
Background: Acute leukemia and hospitalization for hematopoietic stem cell transplantation (HCT) are the great psychological
stressors. The aim of this study was to assess anxiety and depression associated with such conditions and their psychophysical
predictors before and after HCT.
Subjects and methods: We conducted a longitudinal study using self-descriptive tools. The questionnaires: LOT-R, AIS, Mini-
Mac, CECS, RSCL and HADS were filled by 60 patients with acute leukaemia before and after HCT.
Results: Anxiety and depressive symptoms correlated positively with psychological symptom distress. The correlation with
depressive symptoms was weak, however, with anxious symptoms was moderate. In both cases, the higher was a level of
psychological symptom distress, the higher level of anxiety and depression was observed in patients. The results indicated the
weak, positive correlation between onerousness of physical symptoms and a level of anxiety. The greater was the severity of
physical symptoms, the higher was the level of anxiety. The negative predictor of anxious symptoms was control of anxiety but it was
weakly associated with a lower level of the explained variable. The negative predictor of anxious symptoms was also dispositional
optimism whose high level accompanied the lower severity of the explained variable. However, the positive predictor of anxious
symptoms was the variable of onerousness of symptoms whose high level accompanied the higher severity of anxious symptoms in the
examined group
Conclusion: Patients with acute leukemia who are hospitalized for HCT require detailed monitoring of their psychological
distress to introduce the proper psychological and pharmacological interventions that reduce anxiety as well as boost “dispositional
optimism” and mechanisms of control.
Keywords
hematopoietic stem cell transplantation; anxiety; depression; dispositional optimism
Hrčak ID:
263306
URI
Publication date:
4.9.2019.
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