Original scientific paper
INFLUENCE OF THE TYPE OF PLATELETPHERESIS ON THE VALUE OF CORPUSCULAR ELEMENTS IN THE BLOOD DONORS
Elvedin Landžo
; Institute of Transfusion Medicine F BiH (ZZTMFBiH)
Josip Petrović
; University of Mostar, Faculty of Medicine Mostar
Maja Karin
; University of Mostar, Faculty of Medicine Mostar
Ivan Tomić
; University of Mostar, Faculty of Medicine Mostar
Danijel Pravdić
; University of Mostar, Faculty of Medicine Mostar
Abstract
Introduction: During the plateletpheresis procedure the number of trombocites in the donor’s blood significantly decreases, and
the levels of the other components of blood as hematocrit, hemoglobin, and leukocyte diminish as well. Influence of the type of
procedure DN-CFCS and SN-ICFS it is one of the factors that affects the decrease of the levels of HCT, Hgb and WBC. In this study, our goal was to see the difference in the value of HCT, Hgb, WBC, and platelets after the plateletfphresis process between DN-CFCS and SN-IFCS on the same cell separator - Fenval AMICUS.
Donors and methods: The criteria for participation: men between age of 25-45. Two groups were formed. Group I 112
separation done with the method SN-ICFS and Group II 180 separation done with the method DN-CFCS. Statistical analysis:To
confirm the statistical difference we used Student t-test for independent or dependent samples, as well as Mann-Whitney U test as non parametric alternative. The possibility of errors were accepted for α<0.05, and the difference between groups were accepted as statistical relevant for p<0.05.
Results Statistically significant lower values were observed of all researched parameters after separation for the donors on the
equipement Amicus DN, and for donors on Amicus SN. A significant higher value of HCT before procedure was found in the AM DN group, in the researches of the other variables there were no significant differences. The resultst for the comparison of variables after procedure procedure for DN and SN procedure. A significant higher value of HCT and a significant higher level of Hgb, as well as a significant lower level of WBV after procedure in the AM DN group, while for the levels of PLT there were no significant differences.
Conclusion: On the decrease of the value of the observed parameters the type of procedure has an influence that means DNCFCS or SN-IFCS, continuous or discontinuous flow.
Keywords
Comparison of single needle versus double needle platelet, apheresis, donor hematological value
Hrčak ID:
263976
URI
Publication date:
13.9.2017.
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