Professional paper

https://doi.org/10.33004/reumatizam-supp-68-1-1

Classification criteria for systemic lupus erythematosus

Višnja Prus ; Division of Rheumatology, Clinical Immunology and Allergology, Department of Internal Medicine of the Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, University Hospital Centre Osijek, Osijek

Supplements: 00f_PROGRAM.pdf

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease with highly heterogeneous clinical manifestations and of unknown etiology. Due to the need to homogenise different phenotypes (clinical and laboratory) and conduct various clinical studies, in order to better understand and treat this complex disease, different classification tools have been developed and used over the decades – criteria based on the presence of individual disease manifestations and quality indicators in laboratory medicine. Classification tools were often used as auxiliary diagnostic criteria, which is not justified due to their high specificity and low sensitivity. The criteria have changed, they were supplemented and corrected over time, which resulted in a higher level of specificity and sensitivity. The opinion of an expert clinician is still the basis for the diagnosis of SLE, while the purpose of the classification criteria is to form well-defined homogeneous cohorts for further clinical research.

Keywords

Lupus erythematosus, systemic – classification, diagnosis

Hrčak ID:

264285

URI

https://hrcak.srce.hr/264285

Publication date:

14.10.2021.

Article data in other languages: croatian

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