Conference paper
MENTAL STATE AND ITS PSYCHOPHYSICAL CONDITIONS IN PATIENTS WITH ACUTE LEUKAEMIA TREATED WITH BONE MARROW TRANSPLANTATION
Anna Warchala
; Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Ewa Wojtyna
; Institute of Psychology, University of Silesia, Katowice, Poland
Krzysztof Krysta
; Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Abstract
Background: Acute leukaemia and bone marrow transplantation (BMT) as a method of its treatment are great psychological
stressors, which are responsible for anxiety and depression in the group of patients. The aim of the study was to assess the patients’
mental state and its psychophysical predictors before and after BMT.
Subject and method: The study was of a longitudinal and self-descriptive character. The questionnaires: LOT-R, AIS, Mini-Mac,
CECS, RSCL and HADS were filled by 60 patients with acute leukaemia before and after BMT.
Results: There were no essential statistical differences between the severity of anxiety and depression before and after BMT but
the pattern and the power of various mental state predictors changed in the course of the hospitalization. Anxiety before transplantation
was greater when the psychological stress and the strategy of “anxious preoccupation” were stronger and the strategy of
“fighting spirit” and the level of generalized optimism were weaker. The factors explained 51% variations of anxiety before
transplantation. After BMT 77% variations of anxiety were explained, which were associated with a high level of distress at the end
of the hospitalization, higher level of anxiety before transplantation, weaker strategy of “fighting spirit” before transplantation and
stronger strategy of “anxious preoccupation” after BMT. Before transplantation 36% variations of depression were explained and
estimated as weaker “fighting spirit” and worse “global life quality”. The essential predictors of depressive symptoms after transplantation,
explained by 81% variations of depression, were weaker “fighting spirit” before transplantation, stronger “anxious
preoccupation” after transplantation, worse “global life quality” after transplantation and higher level of anxious and depressive
symptoms on admission to hospital.
Conclusion: The psychological and pharmacological interventions, which reduce anxiety, depression and “anxious
preoccupation” as well as enhance “fighting spirit”, should be introduced before BMT to improve the patients’ mental state.
Keywords
bone marrow transplantation; depression; anxiety; coping; figting spirit
Hrčak ID:
264581
URI
Publication date:
8.9.2015.
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