Conference paper

DEPRESSION AND IMMUNITY: THE HCV MODEL

Emanuela Apicella ; Clinic for Eating Disorders “Villa Miralago”, Cuasso al Monte (Va), Italy SUMMARY

Abstract

Available research shows that only some individuals will develop a specific psychiatric disorder in the presence of the same life
events. Different regulation scales are used to define the events that can be considered as stressful and to value their psychological
burden. A personal illness, especially if chronic, is certainly an event characterized by great emotional and psychological impact.
Moreover, symptoms such as mood changes and anxiety, which are commonly observed in patients affected by HCV, can be related
to the awareness of suffering from a chronic progressive disease and to the past or current substance abuse. It is well known that the
assumption of interferon α (IFN α) is associated with the onset of depressive symptoms, similar to those observed in major
depression, in fact, from 30% to 50% of patients receiving IFN develop depression during treatment.Many data in literature show
the very important role of pro-inflammatory cytokines in the onset of the Depression.

Keywords

immunity; depression; HCV

Hrčak ID:

265707

URI

https://hrcak.srce.hr/265707

Publication date:

5.11.2014.

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