Conference paper
REVERSIBLE MILD COGNITIVE IMPAIRMENT - A CASE REPORT
Madhavan Seshadri
; Weller Wing Mental Health Unit, South Essex Partnership University NHS Foundation Trust, Bedford, UK
Nadeem Mazi-Kotwal
; Weller Wing Mental Health Unit, South Essex Partnership University NHS Foundation Trust, Bedford, UK
Mark Agius
; Weller Wing Mental Health Unit, South Essex Partnership University NHS Foundation Trust, Bedford, UK
Abstract
With an increased general practitioner and public awareness, patients are being referred on to Memory Clinics earlier and Mild
Cognitive Impairment (MCI) is often a conclusion of the assessment. The function of memory clinics is to facilitate early and
accurate diagnosis of dementia and its management. Mild Cognitive Impairment is an organic condition which in significant
proportion of cases, progresses to Dementia. In Bedfordshire and Luton, patients with MCI are followed up at nine months to yearly
intervals and detailed neuropsychological assessments are carried out to monitor cognitive functions in order to detect dementia
early and plan care at an early stage in line with the NICE guidance CG42.
An interesting patient presented to the Memory Clinic. He suffered from bipolar disorder with age of onset after 50 years. He
was successfully treated with a combination of antidepressants, antipsychotics and lithium carbonate. He started complaining of
memory difficulties and the initial memory assessment concluded that he had MCI. He was followed up by the clinical psychologist at
memory assessment services at yearly intervals. There were no active cognitive interventions done by the psychologist. In the
meanwhile the patient developed Parkinson’s disease and was treated successfully with levodopa. Following this,
neuropsychological tests demonstrated a significant improvement in cognitive functions. The patient was assessed as having
recovered from mild cognitive disorder.
In this article the authors discuss the possible differential diagnosis and causative factors for the presentation of MCI in this
patient. Furthermore the possible reasons for recovery are explored. This also raised interesting questions as to the pharmacological
management of mild cognitive disorder secondary to neurological conditions and as to how the course of mild cognitive disorders
could be modified by effective interventions.
Keywords
dementia; Mild Cognitive Impairment; MCI; bipolar disorder; Parkinson’s disease; levodopa
Hrčak ID:
266768
URI
Publication date:
26.8.2013.
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