Review article
https://doi.org/10.24869/psyd.2021.485
VERACTIVE BLADDER OR ANXIETY: WHICH CAME FIRST?
Boris Grizelj
; Faculty of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina
Slavko Oreskovic
; Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Mislav Mikus
; Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Vladimir Banovic
; Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Drzislav Kalafatic
; Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Marina Sprem Goldstajn
; Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Abstract
Objective: Although available diagnostic criteria are intelligible, combination of OAB and anxiety in the same patient presents a
perfect example of medical causality dilemma, commonly stated as the question: "which came first: the chicken or the egg?". The
aim of this review article is to address available insights in bidirectional association between OAB and anxiety.
Methods: In this review article, we included different types of studies whose results are presented as relative risk (RR) or odds
ratio (OR) with a 95% accuracy. A literature search was conducted with the use of the PubMed and EMBASE electronic databases
focusing on identifying articles published in English between 1990 and 2020.
Results: The electronic searches, after duplicate records removal, provided a total of 126 citations. Of these, 107 were excluded
after title/abstract screening (not relevant to the review). We examined the full text of 19 publications remaining to summarize
possible mechanisms between OAB and anxiety. According to examined literature, our result synthesis provides insight in
epidemiology, pathophysiology, diagnostic and therapeutic approach of both conditions.
Conclusion: Temporal relationship between OAB and anxiety is not very well documented because available longitudinal cohort
studies are limited. The limitation of the published literature is that most were population-based symptom studies demonstrating high
risk of bias. Although data from analysed studies suggest that anxiety and OAB and anxiety might be casually related, studies
provided on clinical population are warranted. In addition to the traditional urologic factors, we recommend that psychosocial
factors such as anxiety should be assessed routinely in patients with OAB.
Keywords
overactive bladder; anxiety; pathophysiology; treatment
Hrčak ID:
268094
URI
Publication date:
21.12.2021.
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