Original scientific paper
Predictive Parameters of Gestational Diabetes Mellitus
Željka Crnčević-Orlić
Alen Ružić
Bojan Miletić
Oleg Petrović
Luka Zaputović
Tatjana Kehler
Sanjin Rački
Miljenko Kapović
Abstract
Gestational diabetes mellitus is a carbohydrate intolerance recognized in pregnancy. The objective of this study was to
determine the prevalence of gestational diabetes mellitus (GDM) of all deliveries at the University Hospital Rijeka, Croatia
(34 997 deliveries over 10-year period) using 2-hour 75 g oral glucose tolerant test and to evaluate the impact of
GDM on neonatal outcomes and mother’s health. Gestational diabetes was diagnosed in 55 of 128 pregnant women with
suspected glucose intolerance. Logistic regression analysis was used to examine the relationship between fasting plasma
glucose, age, family history, body mass index, maternal weight gain, neonatal weight, neonatal head diameter and Apgar
score in the gestational diabetes group and in the non-diabetes group. The results indicate that fasting plasma glucose
greater than 7.0 mmol/L and maternal overweight are strong predictors for GDM and macrosomia. There was no difference
in the mode of delivery, and vitality and metabolic complications among the infants of all analyzed mothers.We concluded
that to prevent GDM as well as to reduce the rate of macrosomic infants good glycemic control should be initiated
as soon as possible. The 2-hour 75 g OGTT is worth enough to evaluate GDM. Women should be counseled and encouraged
to lose weight before or at the beginning of the conception period.
Keywords
gestational diabetes mellitus; fasting plasma glucose; oral glucose tolerance test
Hrčak ID:
26891
URI
Publication date:
3.9.2007.
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